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Writer's pictureAnirban Biswas

What is cholesterol : What is lipid profile test

Updated: Mar 3, 2023


Lipid profile test
Lipid profile test should be done annually in diabetic patients

What is cholesterol?

Cholesterol is a substance found in the body that is essential for various functions, including the production of hormones, vitamin D, and the digestion of food. It is produced by the liver and can also be obtained through certain foods. While cholesterol is necessary for good health, too much of it can increase the risk of heart disease and stroke. Therefore, it is important to understand the different types of cholesterol, their functions, and how to maintain healthy cholesterol levels through diet and lifestyle changes.

What is Lipid Profile Test?

A lipid profile test is a blood test that measures the levels of various types of fats, or lipids, in the blood. These lipids include cholesterol and triglycerides, and their levels can be used to assess the risk of heart disease and other health conditions.


The lipid profile means " a series of laboratory tests used to assess an individual's cardiovascular health. It measures the levels of lipids including cholesterol and triglycerides in the blood, which are both important indicators of cardiovascular disease risk".

How much does Lipid Profile test cost?


The cost of a Lipid Profile test can vary significantly between various labs. Generally speaking, such tests typically involve a panel of tests measuring total cholesterol, HDL, LDL and triglycerides and can be expected to fall within a range between 450-750 INR USD. At Dr. Anirban Biswas clinic, we perform Free Lipid profile test every month , you can subscribe to our website or check out our events page to get more information regarding Free Lipid profile blood test.

Why is a Lipid Profile Test Important?

High levels of cholesterol and triglycerides can lead to the buildup of fatty deposits in the arteries, which can increase the risk of heart disease and stroke. A lipid profile test can help identify individuals who may be at risk for these conditions, and can be used to guide treatment and lifestyle changes.

What Does a Lipid Profile Test Measure?

A lipid profile test typically measures the following:

Lipid profile test list

  1. Total Cholesterol: This is the total amount of cholesterol in the blood, including both LDL and HDL cholesterol.

  2. LDL Cholesterol: This is often referred to as "bad" cholesterol, as it can contribute to the buildup of fatty deposits in the arteries.

  3. HDL Cholesterol: This is often referred to as "good" cholesterol, as it helps remove LDL cholesterol from the bloodstream.

  4. Triglycerides: These are another type of fat found in the blood, and high levels can increase the risk of heart disease and stroke.

  5. VLDL : VLDL ( Very Low Density Lipoprotein) is produced in the liver and functions in the transportation of fat molecules, making it an important intermediate in lipid metabolism.

In addition to these standard measurements, an extended lipid profile may also measure other types of lipids, such as lipoprotein(a) and remnant lipoproteins. These measurements can provide a more detailed assessment of an individual's risk for heart disease.

What Do the Results of a Lipid Profile Test Mean?

The results of a lipid profile test are typically reported as numerical values, and can vary depending on age, gender, and other factors. In general, the following ranges are considered healthy:

Lipid Profile Normal values:

what is lipid profile
lipid profile normal range

  • Total Cholesterol: less than 200 mg/dL

  • LDL Cholesterol: less than 100 mg/dL

  • HDL Cholesterol: 60 mg/dL or higher

  • Triglycerides: less than 150 mg/dL



However, these ranges may vary depending on an individual's specific risk factors and health history. Therefore, it is important to discuss your lipid profile test report with your healthcare provider, who can help interpret the results and develop a plan for maintaining healthy lipid levels.


What are the signs and symptoms of high cholesterol level?

High cholesterol typically has no signs or symptoms, which is why it's often referred to as a "silent" condition. In some cases, high cholesterol may lead to the development of other health problems, such as heart disease, stroke, or peripheral artery disease. However, there are some physical signs that may indicate high cholesterol levels, including:

  1. Xanthomas: These are yellowish, raised patches of skin that can appear on the back of the ankles, knees, elbows, or buttocks. They are caused by the buildup of cholesterol in the body.

symptoms of high cholesterol
Xanthelesma is fat deposits around eyelips

  1. Xanthelasmas: These are yellowish deposits that can appear on the eyelids. They are also caused by the buildup of cholesterol in the body.



  1. Arcus senilis: This is a white or gray ring that appears around the iris of the eye. It is caused by the buildup of cholesterol in the blood vessels of the eye.

  2. Chest pain: High cholesterol levels can lead to the development of heart disease, which may cause chest pain or discomfort.

  3. Shortness of breath: High cholesterol levels can also increase the risk of developing heart disease, which may cause shortness of breath or difficulty breathing.

It's important to note that these symptoms can also be caused by other health problems and should be evaluated by a healthcare provider. The best way to diagnose high cholesterol is through a blood test.

Diabetes and Lipid Profile Tests

Diabetes can affect lipid levels in the blood, leading to a condition known as diabetic dyslipidemia. In this condition, high blood sugar levels can increase triglyceride levels and decrease HDL cholesterol levels. Therefore, individuals with diabetes may need to have their lipid levels monitored more closely, and may require additional treatment and lifestyle changes to maintain healthy levels.

Cholesterol and Diet

One of the most effective ways to maintain healthy cholesterol levels is through diet. Some foods, such as red meat, full-fat dairy products, and fried foods, are high in saturated and trans fats, which can increase LDL cholesterol levels. On the other hand, foods that are high in fiber, such as fruits, vegetables, whole grains, and legumes, can help lower LDL cholesterol levels. Omega-3 fatty acids found in fatty fish, such as salmon and tuna, can also help increase HDL cholesterol levels. Additionally, maintaining a healthy weight and getting regular physical activity can also help improve cholesterol levels.

Cholesterol and Lifestyle Changes

While high cholesterol levels can be influenced by genetics, they are often a result of lifestyle factors such as a diet high in saturated and trans fats, lack of exercise, and smoking.

In addition to diet, certain lifestyle changes such as eating a healthy diet, exercising regularly, and quitting smoking can help reduce cholesterol levels and lower the risk of heart disease and stroke. In some cases, medication may be necessary to manage high cholesterol levels. However, making lifestyle changes can often be effective in maintaining healthy cholesterol levels and reducing the need for medication.

Cholesterol and heart disease


When cholesterol levels are high, LDL cholesterol, commonly referred to as "bad" cholesterol, can accumulate in the arteries and form plaque. This plaque buildup can cause the arteries to become narrow and less flexible, making it harder for blood to flow to the heart and other organs.


cholesterol and heart disease
High cholesterol is often associated with Heart Attacks

Over time, this buildup can lead to atherosclerosis, a condition in which the arteries become hardened and narrowed due to plaque buildup. Atherosclerosis can cause a range of heart and vascular diseases, including coronary artery disease, stroke, and peripheral artery disease.

In some cases, medication may also be necessary to manage high cholesterol levels. Statins, for example, are a type of medication that can lower cholesterol levels and reduce the risk of heart disease.


Medicines for reducing cholesterol

There are several types of medications that can be used to help reduce LDL cholesterol and increase HDL cholesterol. These medications are usually prescribed by a doctor and should be taken under their supervision. Here are some common types of cholesterol medications:

  1. Statins: Statins are one of the most commonly prescribed medications for lowering LDL cholesterol. They work by inhibiting an enzyme in the liver that produces cholesterol, which leads to a reduction in LDL cholesterol levels. Statins can also modestly increase HDL cholesterol levels.

  2. Bile acid sequestrants: These medications bind to bile acids in the intestines, which helps to prevent the reabsorption of cholesterol into the bloodstream. This can help to lower LDL cholesterol levels.

  3. Nicotinic acid: Nicotinic acid, also known as niacin, is a B vitamin that has been shown to increase HDL cholesterol levels while lowering LDL cholesterol levels. However, it can cause side effects such as flushing and itching.

  4. Fibrates: Fibrates work by reducing the production of triglycerides, a type of fat in the blood that can contribute to heart disease. They can also increase HDL cholesterol levels.

  5. PCSK9 inhibitors: PCSK9 inhibitors are a newer type of medication that work by blocking a protein that regulates LDL cholesterol levels in the blood. By blocking this protein, PCSK9 inhibitors can significantly lower LDL cholesterol levels.

It is important to note that medication should be used in combination with a healthy diet and lifestyle changes for optimal cholesterol management. Speak with your healthcare provider to determine which medication, if any, is right for you. TAKE HOME MESSAGE

Regular cholesterol screenings and lipid profile tests can help identify individuals who may be at risk for heart disease due to high cholesterol levels. By monitoring cholesterol levels and taking steps to manage them, individuals can reduce their risk of heart disease and improve their overall health and well-being. A lipid profile test is a simple blood test that can provide valuable information about an individual's risk for heart disease and other health conditions. By understanding what a lipid profile test is, what it measures, and what the results mean, individuals can take steps to maintain healthy lipid levels and reduce their risk of heart disease and other health conditions.

It is important to note that lipid levels are just one factor that can contribute to overall health and wellness. Other lifestyle factors, such as diet, exercise, and smoking status, also play a role in maintaining a healthy heart and preventing chronic diseases.

If you have not had a lipid profile test recently, talk to your healthcare provider about whether it may be appropriate for you. By monitoring your lipid levels and making appropriate lifestyle changes, you can take steps to protect your heart health and overall well-being.


FREQUENTLY ASKED QUESTIONS

Q1.Is fasting important for lipid profile test ?

A1. Yes, fasting is typically recommended prior to a lipid profile test to ensure accurate results. According to the American Heart Association, fasting for 9-12 hours before a lipid profile test is recommended, as eating or drinking can temporarily affect lipid levels in the blood.

Q2. How often should we do a lipid profile test?

Q3. What are the symptoms of high cholesterol ?

Source:

1. American Heart Association. (2019). Understanding Your Cholesterol Results. Retrieved from https://www.heart.org/en/health-topics/cholesterol/understanding-your-cholesterol-results

2. National Heart, Lung, and Blood Institute. (2002). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Executive Summary. Retrieved from https://www.nhlbi.nih.gov/files/docs/guidelines/atp3xsum.pdf




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